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February 2017

UCLA Bioinformatics Minor Info Session

February 2 @ 4:00 pm - 5:00 pm
Boelter Hall 4760

The UCLA Bioinformatics Minor program encourages all students currently enrolled as program minors as well as those who may be interested in learning more about the Bioinformatics minor as well as research opportunities in Bioinformatics to attend our quarterly information session on Thursday February 2nd from 4-5pm in Boelter Hall 4760. Program faculty, as well as current Bioinformatics undergraduate students involved in research, will host this town hall style meeting to provide information about the bioinformatics minor and information on…

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Barak Cohen Seminar

February 6 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Eric Jellen Seminar

February 13 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Adam Siepel Seminar

February 27 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Abstract:  Transcriptional regulatory changes have been shown to contribute to phenotypic differences between species, but many questions remain about how gene expression evolves. In this talk, I will present the first comparative study of nascent transcription in primates. We used PRO-seq to map actively transcribing RNA polymerases in resting and activated CD4+ T-cells in multiple human, chimpanzee, and rhesus macaque individuals, with rodents as outgroups. This approach allowed us to directly measure active transcription separately from post-transcriptional processes. We observed general…

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March 2017

Michael Beer Seminar

March 6 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Jacques Ravel Seminar

March 13 @ 4:00 pm - 5:00 pm
Boyer Hall 159
April 2017

Markus Covert Seminar

April 3 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Abstract: Our lab recently reported completion of the first "whole-cell" model, explicitly accounting for the known functions of every gene product and molecule in the simplest culturable bacterium, Mycoplasma genitalium.  In this talk I will discuss our efforts to expand this new technology to model more complicated organisms, as well as the applications that we see for such models.

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Brandon Gaut Seminar

April 10 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Plant DNA methylation: An evolutionary perspective Plants methylate the DNA of both transposable elements (TEs) and genes.  For the former, DNA methylation and other epigenetic modifications suppress TE activity.  From studies in several systems, it is now clear that the epigenetic modification of TEs can affect the expression of nearby genes and also that the epigenetic interaction between TEs and their hosts is evolutionarily consequential.  Many of the epigenetic mechanisms that plants use to modify TEs have been characterized, but…

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Zeba Wunderlich Seminar

April 17 @ 4:00 pm - 5:00 pm
Boyer Hall 159

Jun Song Seminar

April 24 @ 4:00 pm - 5:00 pm
Boyer Hall 159
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Upcoming Events

  1. 2nd Annual QCBio Symposium

    April 28 @ 8:30 am - 4:00 pm
  2. Max Diehn Seminar

    May 1 @ 4:00 pm - 5:00 pm
  3. Lea Davis Seminar

    May 8 @ 4:00 pm - 5:00 pm
  4. Ran Libeskind-Hadas Seminar

    May 15 @ 4:00 pm - 5:00 pm
  5. Jo Hardin Seminar

    May 22 @ 4:00 pm - 5:00 pm

Recent Student Publications

Determining the Effect of Natural Selection on Linked Neutral Divergence across Species
Phung TN, Huber CD, Lohmueller KE.
PLOS Genetics. August 2016.

PReFerSim: fast simulation of demography and selection under the Poisson Random Field model
Ortega-Del Vecchyo D, Mardsen CD, Lohmueller KE.
Bioinformatics. July 2016.

SURVIV for survival analysis of mRNA isoform variation
Shen S, Wang Y, Wang C, Wu YN, Xing Y.
Nature Communications. June 2016.