Fine mapping genes for drug action

Project Start Date: Winter 2015
Contact: Des Smith <>
Project Description: Although a staggering array of drugs is available for disorders such as cancer and autoimmunity, much remains unknown about their genetic targets. The project repurposes the technology of radiation hybrid (RH) panels to identify genes for drug action. RH cells contain extra copies of randomly selected genes and offer the opportunity to pinpoint functional drug/gene interactions with high precision. The project involves analyzing the data from these RH mapping experiments to identify gene targets for drugs of medical relevance. Required Experience: The more background in C, Perl and R, the better. Some knowledge of genetic mapping and radiation hybrid mapping desirable.
Possibility of Funding : No

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