Defining human cardiac protein half-life in healthy man and heart failure patients

Project Start Date: Summer 2011
Project Title: Defining human cardiac protein half-life in healthy man and heart failure patients.

Contact: Peipei Ping (

Project Description:
Cell synthesizes proteins and degrades proteins; the half-life of proteins is the key to biological function of all cells. Understanding protein turnover and protein dynamics is essential to developing novel therapies in diseases, including the treatment of heart failure. Using experimental data, this project will develop computational models for predicting the half-life of proteins in healthy individuals and how these protein half-lives maybe impacted in patients suffering from heart failure.

Required Experience: Experience with some programming language (C, C++, Java etc.), some background knowledge of proteins and their half-lives are preferred but not essential.

Possibility of Funding : Yes.

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