Genetics of Neuropsychiatric disorders

Project Start Date: Winter 2012
Project Title: Genetics of Neuropsychiatric disorders
Project Contact: Roel Ophoff (rophoff@mednet.ucla.edu)

Project Description:
Neuropsychiatric disorders are common and can severely disrupt normal life. Despite their high heritability estimates, only a small part of the genetic basis of these disorders has been uncovered. Our lab focuses mostly on schizophrenia, bipolar disorder and amyotrophic lateral sclerosis (ALS). We have begun applying sequencing techniques on different types of human tissue to be able to study different layers of genetic information, including microRNAs, mRNAs, methylation profiles and exomes. The aim of this research direction is shedding light on genetic architecture of neuropsychiatric disorders. These large datasets offer the opportunity to apply either existing methods or develop novel methods and strategies.

Required Experience: Some programming experience.

Possibility of Funding : No

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