Effect of DNA methylation on genomic stability

Project Start Date: Winter 2012

Project Title: Effect of DNA methylation on genomic stability

Project Contact: Guoping Fan (gfan@mednet.ucla.edu)

Project Description:
Dysregulated DNA methylation has been associated with many diseases including cancers, but for reasons that are not well understood. Our lab has developed a model system to assess genomic stability based on different levels of DNA methylation. This project will examine a variety of model systems ranging in yeast, embryonic stem cells, and cancer cells to precisely quantify how DNA methylation contributes to genome stability.

Required Experience: Experience with programming language (Python, Perl, R, Matlab, etc), some background on high-throughput sequencing and epigenetics.

Possibility of Funding: No

Leave a Reply

Your email address will not be published. Required fields are marked *
You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>