Project Start Date: Winter 2012
Project Title: Effect of DNA methylation on genomic stability
Project Contact: Guoping Fan (email@example.com)
Dysregulated DNA methylation has been associated with many diseases including cancers, but for reasons that are not well understood. Our lab has developed a model system to assess genomic stability based on different levels of DNA methylation. This project will examine a variety of model systems ranging in yeast, embryonic stem cells, and cancer cells to precisely quantify how DNA methylation contributes to genome stability.
Required Experience: Experience with programming language (Python, Perl, R, Matlab, etc), some background on high-throughput sequencing and epigenetics.
Possibility of Funding: No