Integrative OMICs methods in neurodegenerative dementia

Project Start Date: Spring 2013
Project Title: Integrative OMICs methods in neurodegenerative dementia.
Project Contact: Giovanni Coppola <gcoppola@ucla.edu>

Project Description:

The long-term goal of our group is to advance our understanding of the genetic architecture of neuropsychiatric disorders. We have collected genetic, genomic (gene expression, methylation) imaging and phenotypic data in a large series of patients with neurodegenerative conditions, including Alzheimer’s Disease (AD) and Frontotemporal Dementia (FTD).

In collaboration with Dr. Horvath, biostatistician at UCLA, and Dr. Paul Thompson (Department of Neurology) we are developing network-based methods to integrate multiple layers of information, including genetic, genomic, epigenetic, and neuroimaging data.

Required Experience: Experience with some programming language (preferred: Python, Perl, R, Java etc.), some background knowledge of biology or genetics

Possibility of Funding : Yes

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